Author

T. Alkutkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:protein structure· 1 Organism:rat· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. B. Ward· 2 shared A. Bukreyev· 1 shared A. Chaudhary· 1 shared A. I. Flyak· 1 shared A. L. Brunh· 1 shared B. Doranz· 1 shared C. D. Murin· 1 shared C. Sou· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

A. B. Ward

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Author profile →

2 papers

Recent·Most cited

Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodies

C. D. Murin, P. Gilchuk, P. Ilinykh, K. Huang, N. Kuzmina, X. Shen, J. F. Brunh, A. L. Brunh, E. Davidson, B. Doranz, L. E. Williamson, J. Copps, T. Alkutkar, A. I. Flyak, A. Bukreyev, , A. B. Ward

The paper presents cryo-EM structures of glycan cap antibodies that neutralize ebolavirus by targeting a conserved MLD-anchor site, revealing common features among broadly neutralizing antibodies.

bioRxiv · Oct 14, 2020Immunology

Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines

L. He, A. Chaudhary, X. Lin, C. Sou, T. Alkutkar, S. Kumar, T. Ngo, E. Kosivner, G. Ozorowski, R. Stanfield, A. B. Ward, I. Wilson, J. Zhu

This study designs and tests Ebola virus vaccines using stabilized GP trimers displayed on nanoparticles, showing they induce neutralizing antibodies and enhance infection.

bioRxiv · Aug 22, 2020Microbiology