P. Yi

Renalase inhibition regulates β cell metabolism to defend against acute and chronic stress

This study shows that inhibiting Renalase protects β cells from stress by shifting metabolism towards glycolysis and GSH synthesis in both mice and humans.

Beta Cells Deficient for Renalase Counteract Autoimmunity by Shaping Natural Killer Cell Activity

This study shows that beta cells lacking Renalase reduce autoimmunity by altering Natural Killer cell activity and enhancing anti-inflammatory responses.

Two subtypes of GTPase-activating proteins coordinate tip growth and cell size regulation in Physcomitrium patens

This study identifies two subtypes of GTPase-activating proteins that regulate tip growth and cell size in moss by modulating ROP activity and membrane organization.

Evaluation of the Abbott ARCHITECT HIV Ag/Ab Combo Assay for Determining Recent HIV-1 Infection

This study evaluates the Abbott ARCHITECT HIV Ag/Ab Combo Assay's ability to determine recent HIV-1 infection using signal-to-cutoff ratios, finding it suitable for both diagnostic and incidence surveillance.

Fast, Efficient, and Precise Gene Editing in the Moss Physcomitrella patens

This paper develops a method for efficient gene editing in the moss Physcomitrella patens using CRISPR/Cas9 and oligonucleotide templates to generate various mutations and enable multiplex gene editing.

MAK and CCRK kinases regulate kinesin-2 motility in C. elegans neuronal cilia

The paper identifies DYF-5 and DYF-18 as regulators of kinesin-2 motility in C. elegans cilia, showing they stabilize IFT particle interactions and prevent ectopic kinesin-II localization.