Author

P. J. Simner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

W. Timp· 2 shared A. Chen· 1 shared A. L. Mammen· 1 shared B. M. Sie· 1 shared B. N. A. Opene· 1 shared C. A. Sherman-Baust· 1 shared C. Bassis· 1 shared C. L. Sears· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMicrobiology

W. Timp

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Author profile →

3 papers

Recent·Most cited

Prevalence, persistence, and genetics of antibody responses to protein toxins and virulence factors

J. W. Angkeow, D. R. Monaco, A. Chen, T. Venkataraman, S. Jayaraman, C. Valencia, B. M. Sie, T. Liechti, P. N. Farhadi, G. Funez-dePagnier, C. A. Sherman-Baust, M. Q. Wong, C. L. Sears, P. J. Simner, J. L. Round, , H. B. Larman

The paper uses PhIP-Seq with a ToxScan library to profile antibody responses to toxins and virulence factors in 1,000 individuals, finding MHC-II locus associations and novel anti-flagellin links to juvenile dermatomyositis.

bioRxiv · Oct 1, 2021 · PreprintImmunology

Metagenomic Next-Generation Sequencing of Rectal Swabs for the Surveillance of Antimicrobial Resistant Organisms on the Illumina Miseq and Oxford MinION Platforms

R. Yee, F. P. Breitwieser, S. Hao, B. N. A. Opene, R. E. Workman, P. D. Tamma, J. Dien Bard, W. Timp, P. J. Simner

This study evaluates mNGS on Illumina MiSeq and Nanopore MinION platforms for detecting MDRO in rectal swabs, showing concordance with culture results and highlighting advantages of both short and long-read approaches.

European Journal of Clinical Microbiology & Infectious Diseases · Aug 11, 2020Peer-reviewedMicrobiology

A plasmid locus associated with Klebsiella clinical infections encodes a microbiome-dependent gut fitness factor

J. Vornhagen, C. Bassis, S. Ramakrishnan, R. Hein, S. Mason, Y. Bergman, N. Sunshine, Y. Fan, W. Timp, M. C. Schatz, V. B. Young, P. J. Simner, M. A. Bachman

The paper identifies a plasmid-encoded ter operon in Klebsiella pneumoniae that functions as a microbiome-dependent gut fitness factor, enhancing colonization in the presence of specific gut microbiota.

bioRxiv · Feb 26, 2020Microbiology