P. Morin

Synaptotoxic forms of amyloid-b and a-synuclein act through a common pathway.

The paper shows that synaptotoxic forms of amyloid-beta and alpha-synuclein act through the same Wnt/PCP pathway to cause dendritic spine loss in neurodegenerative diseases.

ApoE ε4-dependent alteration of CXCR3+CD127+ CD4+ T cells is associated with elevated plasma neurofilament light chain in Alzheimer's disease

The paper finds that ApoE ε4-dependent changes in CXCR3+CD127+ CD4+ T cells in peripheral blood correlate with elevated neurofilament light chain in Alzheimer's disease.

Application of Quasimetagenomics Methods to Define Microbial Diversity and Subtype Listeria monocytogenes in Dairy and Seafood Production Facilities

This study uses 16S rRNA and shotgun quasimetagenomic sequencing to analyze microbial diversity and subtype Listeria monocytogenes in food production facilities, establishing detection thresholds and providing insights for pathogen control.

A role for the autophagic receptor, SQSTM1/p62, in trafficking NF-kB/RelA to nucleolar aggresomes

This paper identifies a novel role for SQSTM1/p62 in trafficking NF-kB/RelA to nucleolar aggresomes under stress, which helps maintain nuclear proteostasis and could inform cancer therapies.

Killer whale genomes reveal a complex history of recurrent admixture and vicariance

This study uses killer whale genomes to reveal complex population history with recurrent admixture and vicariance, showing genetic homogenization at lower latitudes and differentiation at high latitudes.

Identification of a novel, NF-κB nucleolar stress response pathway

The paper identifies a novel NF-κB nucleolar stress response pathway triggered by PolI complex disruption, showing TIF-IA degradation and therapeutic relevance in colorectal tumors.