Author

P. Olinga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 3 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. N. Melgert· 3 shared C. E. Boorsma· 2 shared C. Reker-Smit· 2 shared H. Habibie· 2 shared J. Burgess· 2 shared M. J. R. Ruigrok· 2 shared W. Timens· 2 shared A. Adhyatmika· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersPathology

B. N. Melgert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles.

L. Peters, L. Rakateli, R. Huchzermeier, A. Bonnin-Marquez, S. L. Maas, C. Lin, A. Jans, Y. Geng, A. Gorter, M. Gijbels, S. Rensen, P. Olinga, T. Hendrikx, M. Krawczyk, M. Brisbois, , E. P. C. van der Vorst

This paper shows that miR-26b deficiency worsens MASH in mice, and that miR-26b mimic-loaded LNPs can reverse these effects.

bioRxiv · Feb 18, 2024Pathology

Role of RANKL in Alveolar Epithelial Cell Regeneration: Potential Novel Contributor to Lung Tissue Repair

H. Habibie, S. Song, C. E. Boorsma, K. S. S. Putri, C. Reker-Smit, J. Vlasma, M. J. R. Ruigrok, R. H. Cool, X. Wu, Y. Wang, W. Quax, P. Olinga, C.-A. Brandsma, W. Timens, J. Burgess, B. N. Melgert

This study investigates RANKL's role in lung epithelial cell regeneration, finding it promotes type II alveolar epithelial cell regeneration and may contribute to lung tissue repair.

bioRxiv · Oct 11, 2023 · PreprintCell Biology

Targeted delivery of galunisertib attenuates fibrogenesis in an integrated ex vivo renal transplant and fibrosis model

L. L. van Leeuwen, H. G. D. Leuvenink, B. M. Kessler, P. Olinga, M. J. R. Ruigrok

Galunisertib supplementation during normothermic machine perfusion reduces fibrogenesis without harming renal function.

bioRxiv · Mar 22, 2022 · PreprintBioengineering

Osteoprotegerin expression in liver is induced by IL-13 through TGF-β

A. Adhyatmika, K. S. Putri, E. Gore, K. Mangnus, C. Reker-Smit, D. Schuppan, L. Beljaars, P. Olinga, B. N. Melgert

This study shows IL-13 induces OPG in liver tissue via a TGF-β-dependent pathway involving IL13 receptors and transcription factors STAT6 and AP1.

bioRxiv · Dec 11, 2020 · PreprintPathology

Osteoprotegerin is elevated in pulmonary fibrosis and associates with IPF progression

H. Habibie, K. Putri, C. E. Boorsma, D. Brass, P. Heukels, M. Wijsenbeek-Lourens, M. Kool, M. van der Berge, T. Borghuis, C. A. Brandsma, T. Gan, P. Olinga, W. Timens, N. Kahn, M. Kreuter, , B. N. Melgert

This study shows OPG levels are elevated in fibrotic lung tissue and correlate with IPF disease progression and reduced lung function.

bioRxiv · Dec 2, 2020 · PreprintPathology