Cancer BiologybioRxiv
A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-cell Leukemia
O. Lancho, A. Singh, V. da Silva-Diz…·D. Herranz
This paper identifies a NOTCH1-SIRT1-KAT7 axis in T-ALL that promotes leukemia and resistance to therapy, suggesting new therapeutic targets.
DOI 10.1158/2643-3230.bcd-22-0098