CTLA-4 blockade reverses the Foxp3+ T-regulatory-cell suppression of anti-tuberculosis T-cell effector responses
L. Shao, Y. Gao, X. Shao, Q.-f. Ou, S. Zhang, Q. Liu, B. Zhang, J. Wu, Q. Ruan, L. Shen, X. Weng, W. Zhang, Z. W. Chen
This study shows that blocking CTLA-4 reverses Treg cell suppression of anti-TB T-cell responses in tuberculosis patients.
bioRxiv · May 11, 2020 · PreprintImmunology