Cell BiologybioRxivPreprint
The finger 2 tip loop of Activin A is required for the formation of its non-signaling complex with ACVR1 and type II Bone Morphogenetic Protein receptors
S. Aykul, R. A. Corpina, E. J. Goebel…·V. Idone
The paper shows that the non-signaling complex formed by Activin A and ACVR1 reduces disease severity in FOP by tempering heterotopic ossification.
DOI 10.1101/733147