Author

R. A. Liddle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:zebrafish· 1

Frequent Co-Authors

S. M. Swain· 2 shared A. Kuntze· 1 shared A. M. Martin· 1 shared A. Schlichting· 1 shared A. Schwab· 1 shared A. Stevens· 1 shared B. Fels· 1 shared C. D. Cassilly· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

S. M. Swain

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Piezo1-induced durotaxis of pancreatic stellate cells depends on TRPC1 and TRPV4 channels

I. Budde, A. Schlichting, D. Ing, S. Schimmelpfennig, A. Kuntze, B. Fels, J. M.-J. Romac, S. M. Swain, R. A. Liddle, A. Stevens, A. Schwab, Z. Petho

This study identifies Piezo1, TRPC1, and TRPV4 as mechanosensitive ion channels crucial for durotaxis in pancreatic stellate cells, which contributes to pancreatic cancer progression.

bioRxiv · Dec 22, 2023Physiology

Shear stress-induced pathological changes in endothelial cells occur through Piezo1 activation of TRPV4

S. M. Swain, R. A. Liddle

This study shows that Piezo1 activation by fluid shear stress triggers TRPV4 opening, leading to calcium elevation and endothelial cell dysfunction.

bioRxiv · Jul 1, 2020Cell Biology

Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways

L. Ye, M. Bae, C. D. Cassilly, S. V. Jabba, D. W. Thorpe, A. M. Martin, H.-Y. Lu, J. Wang, J. D. Thompson, C. R. Lickwar, K. D. Poss, D. J. Keating, S.-E. Jordt, J. Clardy, R. A. Liddle, J. F. Rawls

This study identifies a molecular pathway by which enteroendocrine cells respond to bacterial tryptophan catabolites, activating enteric and vagal neurons through Trpa1 signaling.

bioRxiv · Jun 9, 2020Physiology