Author

R. Bostwick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

L. Rasmussen· 3 shared A. Simeonov· 2 shared C. Klumpp-Thomas· 2 shared C. Z. Chen· 2 shared D. C. Lo· 2 shared M. Shen· 2 shared P. Shinn· 2 shared W. Zheng· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

L. Rasmussen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Novel compound inhibitors of HIV-1NL4-3 Vpu

C. A. Robinson, T. D. Lyddon, H. M. Gil, D. T. Evans, Y. V. Kuzmichev, J. Richard, A. Finzi, S. Welbourn, L. Rasmussen, N. M. Nebane, V. V. Gupta, S. Ananthan, Z. Cai, E. R. Wonderlich, C. Augelli-Szafran, , M. C. Johnson

This study identifies two compounds that inhibit HIV-1NL4-3 Vpu activity but are strain-specific.

bioRxiv · Jul 30, 2021Microbiology

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

C. Z. Chen, P. Shinn, Z. Itkin, R. Eastman, R. Bostwick, L. Rasmussen, R. Huang, M. Shen, X. Hu, K. M. Wilson, B. Brooks, H. Guo, T. Zhao, C. Klumpp-Thomas, A. Simeonov, , W. Zheng

The paper identifies 319 compounds with anti-SARS-CoV-2 activities through a high-throughput screen, including 91 approved drugs and 49 investigational drugs, with 230 compounds previously unreported.

bioRxiv · Aug 18, 2020Microbiology

The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators

K. Gorshkov, C. Z. Chen, R. Bostwick, L. Rasmussen, M. Xu, M. Pradhan, B. N. Tran, W. Zhu, K. Shamim, W. Huang, X. Hu, M. Shen, C. Klumpp-Thomas, Z. Itkin, P. Shinn, , W. Zheng

The paper identifies six autophagy modulators that block SARS-CoV-2 cytopathic effects in Vero-E6 cells with EC50 values between 2.0 and 13 µM.

bioRxiv · May 16, 2020Pharmacology & Toxicology