R. Carapito

This study shows that lysosomal positioning in melanoma cells correlates with aggressiveness, promoting invasion and matrix degradation.

This study shows that blood flow enhances the pro-angiogenic effects of tumor-derived extracellular vesicles by altering their intracellular trafficking in endothelial cells.

This study shows that autophagy regulates lipid metabolism in Langerhans cells, preventing their depletion and ferroptosis in the epidermis.

This study shows that blood flow promotes VEGFR signaling in endothelial cells, driving remodeling that facilitates tumor cell extravasation, and that inhibiting VEGFR reduces this process.

This study uses a mouse model to investigate MSU crystal-induced inflammation and identifies imiquimod as a potential therapeutic target for gout by modulating IL-1 expression.

This study shows that blood flow dynamics influence the arrest, adhesion, and extravasation of circulating tumor cells, with implications for metastasis formation.