Endowing Universal CAR T-cell with Immune-Evasive Properties using TALEN-Gene Editing.
S. Jo, S. Das, A. Williams, A.-s. Chretien, T. Pagliardini, A. Leroy, j. postigo-fernandez, D. leclerre, B. jahangiri, i. chion-sotinel, A. Gouble, M. Dusseaux, r. Galetto, a. Duclert, E. Marcenaro, , J. Valton
This paper develops a novel CAR T-cell scaffold with immune-evasive properties to enable universal allogeneic CAR T-cell therapy.
bioRxiv · Dec 6, 2021Immunology