Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
M. Currie, J. Davies, M. Scalise, A. Gulati, J. Wright, M. Newton-Vesty, G. Abeysekera, R. Subramanian, W. Wahlgren, R. Friemann, J. Allison, P. Mace, M. Griffin, B. Demeler, S. Wakatsuki, , R. North
This study reports the cryo-EM structure of a TRAP transporter from Haemophilus influenzae, revealing its dimeric architecture, Na+ sites, and substrate binding site, supported by mutagenic and functional data.
bioRxiv · Aug 28, 2023 · PreprintBiochemistry