Author

J. Allison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Wang· 2 shared P. Sharma· 2 shared S. Basu· 2 shared A. Deswal· 1 shared A. Futreal· 1 shared A. Gulati· 1 shared A. J. Malik· 1 shared A. M. Poole· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

L. Wang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Tertiary-interaction characters enable fast, model-based structural phylogenetics beyond the twilight zone

C. Puente-Lelievre, A. J. Malik, J. Douglas, D. Ascher, M. Baker, J. Allison, A. M. Poole, D. Lundin, M. Fullmer, R. Bouckaert, H. Kim, M. Steinegger, N. J. Matzke

This paper uses tertiary-interaction characters to improve structural phylogenetics beyond the twilight zone, achieving accurate results with fast computation.

bioRxiv · Dec 12, 2023 · PreprintEvolutionary Biology

Molecular pathways and cellular subsets associated with adverse clinical outcomes in overlapping immune-related myocarditis and myositis

B. A. Siddiqui, N. L. Palaskas, S. Basu, Y. Dai, Z. He, S. S. Yadav, J. Allison, R. Sheth, S. Tummala, L. M. Buja, M. Bhattacharjee, C. A. Iliescu, A. Rawther-Karedath, A. Deswal, L. Wang, , S. K. Subudhi

The paper uses single-cell RNA sequencing to identify molecular pathways and immune subsets in immune-related myocarditis and myositis, finding clonally expanded CD8+ T cells and specific myeloid cell populations associated with adverse outcomes.

bioRxiv · Sep 15, 2023Immunology

Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter

M. Currie, J. Davies, M. Scalise, A. Gulati, J. Wright, M. Newton-Vesty, G. Abeysekera, R. Subramanian, W. Wahlgren, R. Friemann, J. Allison, P. Mace, M. Griffin, B. Demeler, S. Wakatsuki, , R. North

This study reports the cryo-EM structure of a TRAP transporter from Haemophilus influenzae, revealing its dimeric architecture, Na+ sites, and substrate binding site, supported by mutagenic and functional data.

bioRxiv · Aug 28, 2023 · PreprintBiochemistry

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

H. A. Abbas, D. Hao, K. Tomczak, P. Baroodia, J. Im, P. K. Reville, Z. Alaniz, W. Wang, R. Wang, F. Wang, G. Al-Atrash, K. Takahashi, J. Ning, M. Ding, J. Matthews, , A. Futreal

This study analyzes single-cell RNA and TCR profiles from AML patients before and after PD-1 blockade therapy to identify factors influencing response and resistance.

bioRxiv · Sep 3, 2020Cancer Biology

Evaluating aerosol and splatter following dental procedures: addressing new challenges for oral healthcare and rehabilitation

J. Allison, C. Currie, D. Edwards, C. Bowes, J. Coulter, K. Pickering, E. Kozhevnikova, J. Durham, C. Nile, N. Jakubovics, N. Rostami, R. Holliday

This study evaluates aerosol and splatter distribution from dental procedures using fluorescein and two analytical methods, finding contamination up to 4 meters with significant reduction via suction.

bioRxiv · Jun 25, 2020Microbiology

Peppy: A Virtual Reality Environment For Exploring The Principles Of Polypeptide Structure

D. Doak, G. Denyer, J. Gerrard, J. Mackay, J. Allison

Peppy is a virtual reality tool designed to teach protein structure principles by allowing interactive exploration of secondary structure factors in a dynamic, 3D environment.

bioRxiv · Aug 8, 2019Biochemistry