Author

R. E. Mardjuki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. A. Carozza· 2 shared L. Li· 2 shared C. Ritchie· 1 shared D. Fernandez· 1 shared G. T. Hess· 1 shared J. A. Brown· 1 shared L. J. Lahey· 1 shared M. C. Bassik· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

J. A. Carozza

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2 papers

Recent·Most cited

BiochemistrybioRxivMay 30, 2020

Structure-aided development of small molecule inhibitors of ENPP1, the extracellular phosphodiesterase of the immunotransmitter cGAMP

J. A. Carozza, J. A. Brown, V. Boehnert…·L. Li

This study develops small molecule ENPP1 inhibitors with sub-nanomolar potency and demonstrates their efficacy in delaying tumor growth in a breast cancer model.

DOI 10.1016/j.chembiol.2020.07.007

mouseexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintFeb 13, 2020

The LRRC8A:C Heteromeric Channel Is a cGAMP Transporter and the Dominant cGAMP Importer in Human Vasculature Cells

L. J. Lahey, X. Wen, R. E. Mardjuki…·L. Li

The paper identifies LRRC8A:C as a cGAMP transporter in human vasculature cells and shows it mediates cGAMP import/export and is the dominant importer in these cells.

DOI 10.1101/2020.02.13.948273

humanexperimental assay

𝕏 PostBluesky