Loss of FSTL1-expressing adipocyte progenitors drives the age-related involution of brown adipose tissue
Z. Huang, Z. Zhang, R. Heck, P. Hu, H. Nanda, K. Ren, Z. Sun, A. Bartolomucci, Y. Gao, D. Chung, W. Zhu, S. Shen, H.-B. Ruan
This study identifies FSTL1-expressing adipocyte progenitors as drivers of age-related brown adipose tissue involution in rabbits and humans, with loss of FSTL1 causing iBAT atrophy in mice.
bioRxiv · May 14, 2020Physiology