R. Hull

Inhibition of hyaluronan synthesis prevents β-cell loss in obesity-associated type 2 diabetes

This study shows that inhibiting hyaluronan synthesis with 4-MU prevents β-cell loss in obesity-associated type 2 diabetes by increasing survivin expression and blocking apoptosis.

Systematic mapping of drug metabolism by the human gut microbiome

The paper systematically maps drug metabolism by the human gut microbiome, showing 13% of 575 drugs are metabolized by a single microbiome sample.