Author

R. J. Karnes

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:multiome· 1

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D. Wang· 1 shared H. Huang· 1 shared I. Coleman· 1 shared J. Zhang· 1 shared L. Ding· 1 shared L. Ma· 1 shared L. Wang· 1 shared P. S. Nelson· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperCancer Biology

D. Wang

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1 paper

Recent·Most cited

Cancer BiologybioRxivApr 10, 2018

EZH2 co-opts gain-of-function p53 mutants to promote cancer growth and metastasis

Y. Zhao, L. Ding, D. Wang…·H. Huang

This study identifies EZH2 as a p53 mRNA-binding protein that enhances translation of gain-of-function p53 mutants, promoting cancer growth and metastasis, and shows that inhibiting EZH2 causes synthetic lethality in these cells.

DOI 10.15252/embj.201899599

humanmultiome

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