Author

R. Kuskovsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

H. Jiang· 2 shared K. M. Aird· 2 shared M. T. Doan· 2 shared N. W. Snyder· 2 shared R. Buj· 2 shared A. Bostwick· 1 shared C. Mesaros· 1 shared C.-W. Chen· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

H. Jiang

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2 papers

Recent·Most cited

Suppression of p16 increases nucleotide synthesis via mTORC1

R. Buj, C.-W. Chen, E. S. Dahl, K. E. Leon, R. Kuskovsky, N. Maglakelidze, M. Navaratnarajah, G. Zhang, M. T. Doan, H. Jiang, M. Zaleski, L. Kutzler, H. Lacko, Y. Lu, G. B. Mills, , K. M. Aird

This study shows that p16 suppression increases nucleotide synthesis through mTORC1 activation, promoting tumorigenesis by bypassing senescence.

bioRxiv · Jul 20, 2019Cancer Biology

Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry

R. Kuskovsky, R. Buj, P. Xu, S. Hofbauer, M. T. Doan, H. Jiang, A. Bostwick, C. Mesaros, K. M. Aird, N. W. Snyder

This paper develops a method to simultaneously quantify and trace dNTP metabolites using isotope dilution and high-resolution mass spectrometry, showing improved accuracy and metabolic pathway insights.

bioRxiv · Oct 29, 2018Biochemistry