Cell BiologybioRxivPreprint
A lysosomal surveillance response (LySR) that reduces proteotoxicity and extends healthspan
T. Y. Li, A. W. Gao, X. Li…·J. Auwerx
This paper identifies a lysosomal surveillance response (LySR) that reduces proteotoxicity and extends healthspan in worms and mammalian cells by enhancing protein aggregate clearance.
DOI 10.1101/2022.06.13.495962