R. O. C. Oreffo

This study evaluates bioactive coatings on 3D printed PCL-TMA900 scaffolds for bone regeneration using a murine femur defect model, finding that Laponite/BMP-2 coating significantly promotes bone formation without heterotopic bone formation.

This paper evaluates Laponite-coated scaffolds for delivering BMP-2 to enhance bone regeneration, showing effective osteoinduction in vitro and in vivo with delayed use.

This study evaluates bioactive coatings on 3D-printed PCL-TMA scaffolds for bone regeneration, showing in vitro osteogenic response but no significant in vivo bone formation.

This paper develops a nanocomposite bioink using human bone extracellular matrix, nanoclay, and alginate for 3D bioprinting to support osteogenic differentiation of bone marrow stromal cells in vitro and ex vivo.

The paper uses single-cell RNA sequencing to identify new targets for isolating skeletal stem cells from human bone marrow using DNA-coated gold nanoparticles.

This study shows that osteoclast-derived extracellular vesicles promote sensory neuron sprouting and electrophysiology via EGFR activation.

This paper isolates and enriches skeletal stem cells (SSCs) from human bone marrow using DNA-gold nanoparticles targeting specific mRNA signatures.