Cell BiologybioRxiv
Single-cell transcriptomics reveal distinctive patterns of fibroblast activation in murine heart failure with preserved ejection fraction
J. D. Lanzer, L. M. Wienecke, R. O. Ramirez-Flores…·F. Leuschner
This study uses single-cell RNAseq to identify distinct fibroblast and macrophage activation patterns in murine HFpEF, revealing disease-specific transcriptional signatures and a potential biomarker.