Author

R. Rizzuto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Hermant· 1 shared A. Martinez-Sanchez· 1 shared A. Weiser· 1 shared B. Blaauw· 1 shared B. Brinon· 1 shared C. Mammucari· 1 shared D. A. Jacobson· 1 shared D. Bano· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperPhysiology

A. Hermant

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis

M. Vetralla, L. Wischhof, V. Cadenelli, E. Scifo, D. Ehninger, R. Rizzuto, D. Bano, D. De Stefani

This study identifies TMEM65 as a key component of the mitochondrial Ca2+ efflux machinery, showing its role in maintaining Ca2+ homeostasis and preventing mitochondrial dysfunction.

bioRxiv · Oct 10, 2023Biochemistry

Mitochondrial Calcium Uptake Declines during Aging and is Directly Activated by Oleuropein to Boost Energy Metabolism and Skeletal Muscle Performance

G. Gherardi, A. Weiser, F. Bermont, E. Migliavacca, B. Brinon, G. E. Jacot, A. Hermant, M. Sturlese, L. Nogara, D. Barron, B. Blaauw, S. Moro, R. Rizzuto, J. N. Feige, C. Mammucari, U. DeMarchi

This study identifies Oleuropein as a MCU activator that enhances mitochondrial function and muscle performance in both young and aged organisms.

bioRxiv · Feb 24, 2023Physiology

The mitochondrial Ca2+ uniporter MCU is required for normal glucose-stimulated insulin secretion in vitro and in vivo

E. Haythorne, E. Georgiadou, M. Dickerson, L. Lopez Noriega, T. J. Pullen, G. da Silva Xavier, S. Davis, A. Martinez-Sanchez, F. Semplici, R. Rizzuto, J. A. McGinty, P. M. French, M. C. Cane, D. A. Jacobson, I. Leclerc, G. A. Rutter

This study shows that the mitochondrial Ca2+ uniporter MCU is essential for normal glucose-stimulated insulin secretion in pancreatic beta-cells, both in vitro and in vivo.

bioRxiv · Sep 25, 2019Physiology