ImmunologybioRxiv
The lupus susceptibility locus Sgp3 encodes the suppressor of endogenous retrovirus expression SNERV
R. S. Treger, S. D. Pope, Y. Kong…·A. Iwasaki
This study identifies SNERV, a suppressor of endogenous retrovirus expression, as a lupus susceptibility gene, showing its role in preventing ERV overexpression and associated nephritis.
DOI 10.1016/j.immuni.2018.12.022