PI4KIII3β inhibition reduces rhinovirus associated cell shedding and ciliary dysfunction
S. Velkova, A. Petris, D. Lee, D. Cardinale, D. Moulding, R. Williamson, S. Beinke, K. Grace, E. Hessel, N. Belyaev, T. Hoegg, J. Hurst, R. Smyth, C. Smith, P. Freestone, C. O'Callaghan
This study shows that inhibiting PI4KIIIβ reduces rhinovirus replication and ciliated cell loss in respiratory epithelial cultures from healthy and COPD patients.
bioRxiv · Dec 14, 2023 · PreprintCell Biology