BiophysicsbioRxivPreprint
Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator
B. E. Krumm, J. F. DiBerto, R. H. J. Olsen…·B. L. Roth
This study reveals the cryoEM structures of NTSR1 with and without SBI-553, showing its biased allosteric modulation of G protein and β-Arrestin signaling.
DOI 10.1101/2022.12.26.521971