Author

S. Akashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:cryo-EM· 1 Organism:E. coli· 1 Organism:plant (other)· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Nagadoi· 1 shared C. Tsuchiya· 1 shared C.-Y. Ye· 1 shared D. Wu· 1 shared E. Chikaishi· 1 shared E. Luk· 1 shared H. Akutsu· 1 shared H. Kurumizaka· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

A. Nagadoi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NMR analysis of the homodimeric structure of a D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria

T. Konuma, T. Takai, C. Tsuchiya, M. Nishida, M. Hashiba, Y. Yamada, H. Shirai, A. Nagadoi, E. Chikaishi, K.-i. Akagi, S. Akashi, T. Yamazaki, H. Akutsu, T. Ikegami

The paper determines the dimeric structure of VanX using NMR and identifies a monomeric form for inhibitor screening.

bioRxiv · Oct 13, 2023Biochemistry

Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP

Y. Imaizumi, K. Takanuki, T. Miyake, M. Takemoto, K. Hirata, M. Hirose, R. Oi, T. Kobayashi, K. Miyoshi, R. Aruga, T. Yokoyama, S. Katagiri, H. Matsuura, K. Iwasaki, T. Kato, , T. Nogi

This study elucidates the mechanism of intramembrane proteolysis by E. coli RseP through crystal structures and mutational analysis, revealing a gating mechanism for substrate entry.

bioRxiv · Jan 31, 2022Biochemistry

Horizontal Transfers Lead to the Birth of Momilactone Biosynthetic Gene Clusters in Grass

D. Wu, Y. Hu, S. Akashi, H. Nojiri, C.-Y. Ye, Q.-H. Zhu, K. Okada, L. Fan

This study shows that horizontal gene transfer created momilactone biosynthetic gene clusters in grasses, with subsequent gene recruitment and loss shaping their evolution.

bioRxiv · Jan 11, 2022 · PreprintEvolutionary Biology

Cryo-electron microscopy structure of the H3-H4 octasome without histones H2A and H2B

K. Nozawa, Y. Takizawa, L. Pierrakeas, K. Saikusa, S. Akashi, E. Luk, H. Kurumizaka

The paper determines the cryo-EM structures of the H3-H4 octasome in two conformations, revealing its unique DNA wrapping and H4-H4 interface.

bioRxiv · Oct 27, 2021 · PreprintBiochemistry