S. Alonso-Gil

This study determines the structure of CFAP410's C-terminal domain and shows that its tetrameric helical bundle is essential for basal body localization, explaining how the L224P mutation causes ciliopathies.

This study reports the crystal structure of the N-terminal domain of CFAP410 and shows how mutations in this domain disrupt its structural stability and interaction with partners, leading to disease.

This study shows that reduced Ambra1 levels in mice lead to metabolic issues and faster retinal degeneration, suggesting autophagy's role in protecting against aging-related vision loss.