Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation
J. D. Daley, E. Mukherjee, A. C. Tufino, N. Bailey, S. Bhaskar, N. Periyapatna, I. MacFawn, S. Kunning, C. Hinck, T. Bruno, A. C. Olson, L. M. Mcallister, A. P. Hinck, K. Cooper, R. Bao, , K. M. Bailey
The paper develops an immunocompetent mouse model of Ewing sarcoma to show that TGFβ inhibition enhances immune infiltration and reduces metastasis during radiation therapy.
bioRxiv · May 7, 2024 · PreprintCancer Biology