Author

S. Boland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Jekle· 2 shared A. Marchand· 2 shared A. Stoycheva· 2 shared C. Liu· 2 shared D. Bardiot· 2 shared D. Jochmans· 2 shared J. A. Symons· 2 shared J. Deval· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Jekle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The substitutions L50F, E166A and L167F in SARS-CoV-2 3CLpro are selected by a protease inhibitor in vitro and confer resistance to nirmatrelvir

D. Jochmans, C. Liu, K. Donckers, A. Stoycheva, S. Boland, S. K. Stevens, C. De Vita, B. Vanmechelen, P. Maes, B. S. Trüeb, N. Ebert, V. Thiel, S. De Jonghe, L. Vangeel, D. Bardiot, , K. Vandyck

This paper identifies three substitutions in SARS-CoV-2 3CLpro that confer resistance to nirmatrelvir and other 3CLpro inhibitors in vitro.

bioRxiv · Jun 7, 2022 · PreprintMicrobiology

Progranulin deficiency results in reduced bis(monoacylglycero)phosphate (BMP) levels and gangliosidosis

S. Boland, S. Swarup, Y. A. Ambaw, R. C. Richards, A. W. Fischer, S. Singh, G. Aggarwal, S. Spina, A. L. Nana, L. T. Grinberg, W. W. Seeley, M. A. Surma, C. Klose, J. A. Paulo, A. D. Nguyen, , R. V. Farese

This study shows that progranulin deficiency reduces bis(monoacylglycero)phosphate levels, leading to gangliosidosis and neurodegeneration.

bioRxiv · Sep 30, 2021Cell Biology

Co-culture of type I and type II pneumocytes as a model of alveolar epithelium

O. Brookes, S. Boland, R. Lai-Kuen, A. Baeza-Squiban

This study develops a co-culture model of type I and type II pneumocytes to better represent alveolar epithelium function and barrier properties.

bioRxiv · Mar 8, 2021Cell Biology

ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model

K. Vandyck, R. Abdelnabi, K. Gupta, D. Jochmans, A. Jekle, J. Deval, D. Misner, D. Bardiot, C. S. Foo, C. Liu, S. Ren, L. Beigelman, L. M. Blatt, S. Boland, L. Vangeel, , J. Neyts

This study evaluates ALG-097111, a selective SARS-CoV-2 3CLpro inhibitor, showing potent in vitro activity and significant in vivo antiviral effects in Syrian hamsters.

bioRxiv · Feb 14, 2021Microbiology