S. Swarup

Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST

This study uses nMOST to profile proteo-lipidomics in lysosomal storage disease mutants, revealing autophagy defects and mitochondrial dysfunction.

High methane flux in a tropical peatland post-fire is linked to homogenous selection of diverse methanogenic archaea

The paper examines how fire affects peatland microbiomes and methane-producing archaea, showing predictable shifts in community composition post-fire.

Quantitative mapping of autophagic cargo during nutrient stress reveals YIPF3-YIPF4 as membrane receptors for Golgiphagy

The paper identifies YIPF3 and YIPF4 as membrane receptors for Golgiphagy during nutrient stress and shows their role in autophagic degradation of Golgi proteins.

Early Endosome Capture Proteomics and its Application to Amyloid Precursor Protein Intramembrane Processing by β and γ-Secretases

This paper develops a method to isolate early endosomes and uses it to study amyloid precursor protein processing by β and γ-secretases in these compartments.

Progranulin deficiency results in reduced bis(monoacylglycero)phosphate (BMP) levels and gangliosidosis

This study shows that progranulin deficiency reduces bis(monoacylglycero)phosphate levels, leading to gangliosidosis and neurodegeneration.

Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

This study identifies TAX1BP1 as essential for lysophagy by using proteomics and flux reporters to show its role in damaged lysosome turnover.

Integrative systems approach reveals dynamics of microbiome-metal-ion axis in mesocosms representing tropical urban freshwater canal ecosystem

The paper develops a systems framework to study interactions between macro-organisms, sedimentary microbes, and geochemistry in tropical urban canals after rainfall disturbances.

Crosskingdom growth benefits of fungus-derived phytohormones in Choy Sum

This study identifies fungus-derived phytohormones from Penicillium citrinum that promote Choy Sum growth through volatile metabolites and hormone-like compounds.

Extracellular Electron Transfer Powers Enterococcus faecalis Biofilm Metabolism

This study identifies a novel iron-dependent extracellular electron transfer (EET) mechanism in Enterococcus faecalis biofilms that enhances growth and matrix properties.