Author

S. Spina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. L. Nana· 2 shared L. T. Grinberg· 2 shared W. W. Seeley· 2 shared A. D. Nguyen· 1 shared A. J. Ehrenberg· 1 shared A. L. Nolan· 1 shared A. M. Karydas· 1 shared A. R. Argouarch· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

A. L. Nana

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Progranulin deficiency results in reduced bis(monoacylglycero)phosphate (BMP) levels and gangliosidosis

S. Boland, S. Swarup, Y. A. Ambaw, R. C. Richards, A. W. Fischer, S. Singh, G. Aggarwal, S. Spina, A. L. Nana, L. T. Grinberg, W. W. Seeley, M. A. Surma, C. Klose, J. A. Paulo, A. D. Nguyen, , R. V. Farese

This study shows that progranulin deficiency reduces bis(monoacylglycero)phosphate levels, leading to gangliosidosis and neurodegeneration.

bioRxiv · Sep 30, 2021Cell Biology

A systematic comparison of fibroblasts derived from postmortem human dura mater versus dermal epithelium for neurodegenerative disease modeling

A. R. Argouarch, C. G. Cosme, K. Garcia, C. I. Corrales, A. L. Nana, A. M. Karydas, S. Spina, L. T. Grinberg, B. Miller, H. Goodarzi, W. W. Seeley, A. W. Kao

This study compares fibroblasts from postmortem human dura mater and dermal epithelium, finding significant differences in morphology, growth, marker expression, and chromosomal abnormalities.

bioRxiv · May 17, 2021 · PreprintCell Biology

Alzheimer’s disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation

C. Petersen, A. L. Nolan, E. d. P. F. Resende, Z. Miller, A. J. Ehrenberg, M. L. Gorno-Tempini, H. J. Rosen, J. H. Kramer, S. Spina, G. D. Rabinovici, B. L. Miller, W. Seeley, Z. Miller, H. Heinsen, L. Grinberg

This study examines how different clinical variants of Alzheimer’s disease correlate with distinct regional patterns of neurofibrillary tangle accumulation in the brain.

bioRxiv · Apr 9, 2019Pathology