Heterodimers of functionally divergent ARF-GEF paralogues prevented by self-interacting dimerisation domain
G. Jürgens, S. Brumm, H. Beckmann, S. Richter, M. K. Singh, K. Huhn, T. Kucera, S. Baumann, C. Kriechbaum, H. Wolters, S. Takada
The paper shows that GNOM and GNL1 ARF-GEFs form homodimers but not heterodimers due to self-interacting dimerisation domains, preventing potentially harmful interactions.
bioRxiv · Sep 14, 2021 · PreprintPlant Biology