S. K. Rai

The paper uses single-molecule techniques to study phase separation of a prion-like domain, revealing structural subpopulations and molecular events involved in condensate formation and disease-related aggregation.

This paper introduces an AI-powered nanopore sequencing method to measure DNA replication stress in cancer cells, showing it can distinguish fork slowing from stalling and detect therapy-specific replication stress signatures.

This study shows that tau and prion proteins form dynamic condensates through electrostatic interactions, which can transition into solid-like co-aggregates with age.

This study investigates how prion protein and α-synuclein form dynamic condensates that influence phase transitions and amyloid conversion through electrostatic interactions and RNA effects.

This study shows that the Y145Stop variant of the prion protein undergoes liquid-liquid phase separation and transitions into amyloid-like aggregates, highlighting a potential role for intrinsically disordered regions in neurodegenerative diseases.