Author

S. McLean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:metagenomics· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Dagenais· 1 shared A. J. Robison· 1 shared A. Kaya· 1 shared A. Kozak· 1 shared A. M. Varney· 1 shared A. Mendenhall· 1 shared A. Mershin· 1 shared A. Tyshkovskiy· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. Dagenais

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Author profile →

4 papers

Recent·Most cited

Evaluation of phenotypic and genotypic methods for the identification and characterisation of bacterial isolates recovered from catheter-associated urinary tract infections

A. M. Varney, E. Mannix-Fisher, J. C. Thomas, S. McLean

The paper evaluates phenotypic and genotypic methods for identifying and characterizing bacterial isolates from catheter-associated urinary tract infections, finding no consensus across methods and highlighting the importance of whole genome sequencing for accurate identification.

bioRxiv · Dec 11, 2023Microbiology

Interleukin-10-producing monocytes contribute to sex differences in pain resolution in mice and humans.

J. Sim, E. O'Guin, K. Monahan, C. Sugimoto, S. McLean, L. Albertorio-Saez, Y. Zhao, A. Dagenais, S. Laumet, M. Bernard, J. K. Folger, A. J. Robison, S. D. Linnstaedt, G. Laumet

The paper shows that male mice and humans have higher IL-10-producing monocytes, which correlate with faster pain resolution, and that androgens drive this sex difference.

bioRxiv · Nov 3, 2023Immunology

Evidence that conserved essential genes are enriched for pro-longevity factors

N. Oz, E. Vayndorf, M. Tsuchiya, S. McLean, L. Turcios-Hernandez, J. N. Pitt, B. W. Blue, M. Muir, M. G. Kiflezghi, A. Tyshkovskiy, A. Mendenhall, M. Kaeberlein, A. Kaya

The paper shows that overexpressing conserved essential genes in yeast increases replicative lifespan more than deleting them, suggesting essential genes are important for longevity.

bioRxiv · Mar 18, 2022Cell Biology

Feasibility of Integrating Canine Olfaction with Chemical and Microbial Profiling of Urine to Detect Lethal Prostate Cancer

C. Guest, R. Harris, K. S. Sfanos, E. Shrestha, A. W. Partin, B. Trock, L. Mangold, R. Bader, A. Kozak, S. Mclean, J. Simons, H. Soule, T. Johnson, W.-Y. Lee, Q. Gao, , A. Mershin

This study tests the feasibility of using canine olfaction, VOC analysis, and microbial profiling in urine to detect lethal prostate cancer, showing 71% sensitivity and 70-76% specificity.

bioRxiv · Sep 9, 2020Cancer Biology