Author

J. Sim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:yeast· 2

Frequent Co-Authors

A. P. Joglekar· 2 shared B. Roy· 2 shared A. Albakri· 1 shared A. Blanco· 1 shared A. Dagenais· 1 shared A. Fontan· 1 shared A. J. Robison· 1 shared A. Rathod· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCell Biology

A. P. Joglekar

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Interleukin-10-producing monocytes contribute to sex differences in pain resolution in mice and humans.

J. Sim, E. O'Guin, K. Monahan, C. Sugimoto, S. McLean, L. Albertorio-Saez, Y. Zhao, A. Dagenais, S. Laumet, M. Bernard, J. K. Folger, A. J. Robison, S. D. Linnstaedt, G. Laumet

The paper shows that male mice and humans have higher IL-10-producing monocytes, which correlate with faster pain resolution, and that androgens drive this sex difference.

bioRxiv · Nov 3, 2023Immunology

β-carotene accelerates the resolution of atherosclerosis in mice

I. Pinos, J. Coronel, A. Albakri, A. Blanco, P. McQueen, D. Molina, J. Sim, E. A. Fisher, J. Amengual

This study shows that β-carotene accelerates atherosclerosis resolution in mice without affecting body weight or plasma lipid levels.

bioRxiv · Mar 7, 2023Immunology

Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses

M. J. Howlader, W. G. Ambler, M. L. S. Chalasani, A. Rathod, E. Seltzer, J. Sim, J. Shin, N. Schwartz, W. D. Shipman, D. Dasoveanu, C. Carballo, E. Sevim, S. Siddique, Y. Chinenov, S. Rodeo, , T. T. Lu

This study shows that lymphatic dysfunction in lupus exacerbates cutaneous photosensitivity and lymph node B cell responses, and that improving lymphatic flow reduces these effects.

bioRxiv · Jun 13, 2022Immunology

ECPAS/Ecm29-Mediated 26S Proteasome Disassembly Is an Adaptive Response to Glucose Starvation

W. H. Choi, Y. Yun, I. Byun, S. Lee, J. Sim, S. Levi, S. Kim, S. H. Park, J. Jun, K. P. Kim, Y. T. Kwon, D. Han, T. Chiba, C. Seok, M. H. Glickman, M. J. Lee

This study shows that ECPAS-mediated 26S proteasome disassembly into 20S and 19S subcomplexes occurs during glucose starvation, enhancing proteolysis and cell survival.

bioRxiv · Jun 6, 2022Biochemistry

Kre28-Spc105 interaction is essential for Spc105 loading at the kinetochore.

B. Roy, J. Sim, S. J. Y. Han, A. P. Joglekar

This study shows that the Kre28-Spc105 interaction is essential for Spc105 recruitment at the kinetochore, which is necessary for proper chromosome biorientation and segregation.

bioRxiv · Sep 12, 2021Cell Biology

Minimization of cross-talk between mitotic Checkpoint silencing and error correction

B. Roy, V. Verma, J. Sim, A. Fontan, A. P. Joglekar

The paper shows that yeast kinetochores use separate PP1 sources and delay SAC silencing to prevent cross-talk between checkpoint silencing and error correction, ensuring accurate chromosome segregation.

bioRxiv · Jun 10, 2019Cell Biology