Author

S. Rane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Yates· 3 shared B. Seddon· 2 shared A. J. Yates· 1 shared A. Khosravi· 1 shared A. Olin· 1 shared C. Pearson· 1 shared E. Lee· 1 shared G. Possnert· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

A. Yates

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4 papers

Recent·Most cited

Notch2 signaling guides B cells away from germinal centers towards marginal zone B cell and plasma cell differentiation

T. Babushku, M. Lechner, A. Yates, S. Rane, U. Zimber-Strobl, L. J. Strobl

The paper shows Notch2 signaling drives B cells from germinal centers to become marginal zone B cells or plasma cells, with mathematical modeling supporting this pathway.

bioRxiv · Jun 13, 2022Immunology

Towards a unified model of naive T cell dynamics across the lifespan

S. Rane, T. Hogan, E. Lee, B. Seddon, A. Yates

This study develops a unified model of naive CD4 and CD8 T cell dynamics across the mouse lifespan, revealing that survival capacity increases with age and that naive CD8 T cells are rapidly lost early in life.

bioRxiv · Jan 7, 2022Immunology

Fate mapping quantifies the dynamics of B cell development and activation throughout life

M. Verheijen, S. Rane, C. Pearson, A. J. Yates, B. Seddon

This study uses fate mapping in mice to show differences in B cell dynamics between follicular and germinal center cells across life.

bioRxiv · Feb 25, 2020Immunology

Cell Generation Dynamics Underlying Naïve T Cell Homeostasis in Adult Humans

J. Mold, P. Reu, A. Olin, S. Bernard, J. Michaëlsson, S. Rane, A. Yates, A. Khosravi, M. Salehpour, G. Possnert, P. Brodin, J. Frisen

This study measures age-related changes in naive T cell turnover using 14C dating and identifies NF-κB signaling as critical for homeostatic proliferation.

bioRxiv · May 13, 2019 · PreprintImmunology