Author

U. Zimber-Strobl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Vincent-Fabert· 2 shared J. Feuillard· 2 shared N. Faumont· 2 shared A. David· 1 shared A. Saintamand· 1 shared A. Yates· 1 shared C. Qiu· 1 shared F. Boyer· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

C. Vincent-Fabert

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4 papers

Recent·Most cited

Notch2 signaling guides B cells away from germinal centers towards marginal zone B cell and plasma cell differentiation

T. Babushku, M. Lechner, A. Yates, S. Rane, U. Zimber-Strobl, L. J. Strobl

The paper shows Notch2 signaling drives B cells from germinal centers to become marginal zone B cells or plasma cells, with mathematical modeling supporting this pathway.

bioRxiv · Jun 13, 2022Immunology

Pre-Clinical Blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma.

C. Vincent-Fabert, L. Roland, U. Zimber-Strobl, J. Feuillard, N. Faumont

The paper shows that blocking PD-L1 in a mouse model of activated B-cell lymphoma leads to tumor regression, suggesting potential for PD-1/PD-L1 axis therapies combined with tyrosine kinase inhibitors.

bioRxiv · Dec 21, 2018Cancer Biology

Reproducing Transformation of Indolent B-cell Lymphoma by T-cell Immunosuppression of L.CD40 Mice.

C. Vincent-Fabert, A. Saintamand, A. David, M. Alizadeh, F. Boyer, N. Arnaud, U. Zimber-Strobl, J. Feuillard, N. Faumont

The paper shows that T-cell immunosuppression in L.CD40 mice transforms indolent B-cell lymphoma into an aggressive form, highlighting immune surveillance's role in disease progression.

bioRxiv · Nov 24, 2018Cancer Biology

Jagged1/Notch2 Controls Kidney Fibrosis via Tfam-mediated Metabolic Reprogramming

S. Huang, J. Park, C. Qiu, Y. Sirin, S. H. Han, S.-y. Li, V. Taylor, U. Zimber-Strobl, K. Susztak

This study identifies Jag1/Notch2 as a key driver of kidney fibrosis through Tfam-mediated metabolic reprogramming in mouse models.

bioRxiv · Mar 29, 2018Pathology