Author

S. Riffault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

D. Descamps· 3 shared B. Correia· 2 shared C. Yang· 2 shared F. Sesterhenn· 2 shared J. Bonet· 2 shared J.-f. Eleouet· 2 shared M. Galloux· 2 shared M.-A. Rameix-Welti· 2 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

D. Descamps

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The microbiota plays a critical role in the reactivity of lung immune components to innate ligands

Q. Marquant, D. Laubreton, C. Drajac, E. Mathieu, E. Bouguyon, M.-L. Noordine, A. Remot, S. Riffault, M. Thomas, D. Descamps

This study shows that the presence of microbiota in SPF mice reduces lung inflammation compared to GF mice when exposed to pathogen stimuli.

bioRxiv · Oct 19, 2020Immunology

De novo protein design enables precise induction of functional antibodies in vivo

F. Sesterhenn, C. Yang, J. Cramer, J. Bonet, X. Wen, L. Abriata, I. Kucharska, C.-I. Chiang, Y. Wang, G. Castoro, S. Vollers, M. Galloux, R. Charles-Adrien, E. Dheilly, S. Rosset, , B. Correia

This paper introduces a de novo protein design algorithm called TopoBuilder that generates immunogens inducing precise antibody responses against respiratory syncytial virus in mice and non-human primates.

bioRxiv · Feb 14, 2020 · PreprintBioengineering

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

F. Sesterhenn, M. Galloux, S. S. Vollers, L. Csepregi, C. Yang, D. Descamps, J. Bonet, S. Friedensohn, P. Gainza, P. Corthesy, M. Chen, S. Rosset, M.-A. Rameix-Welti, J.-F. Eleouet, S. T. Reddy, , B. Correia

This study demonstrates that a computationally designed epitope-focused immunogen enhances subdominant neutralizing antibody responses against RSV.

bioRxiv · Nov 22, 2018Immunology