T. A. Reese

This study identifies a mechanism by which norovirus induces cell death and egress through an MLKL-like pore-forming protein that targets mitochondria.

This study shows that intestinal parasite infection expands resident macrophages via retinoic acid signaling, leading to increased herpesvirus infection and reactivation.

This study identifies CDKL5 as a regulator of virophagy, showing it promotes p62-mediated autophagy of viral capsids and enhances antiviral defense.

This study shows that PPAR agonists like WY14643 increase herpesvirus replication and inhibit IFNβ production, independent of PPARα expression.

This study shows that IL-4 induces MHV68 reactivation in macrophages but not B cells, indicating cell-type specific regulation of herpesvirus reactivation.

This study shows that PPAR-α activation increases herpesvirus replication, suppresses type I interferon, and inhibits STING signaling through ROS.