S. Sukumar

Myoferlin is an essential component of late-stage vRNP trafficking vesicles for enveloped RNA viruses.

The paper identifies myoferlin as a conserved host factor essential for late-stage vRNP trafficking in enveloped RNA viruses like IAV, RSV, and SeV.

Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking

The paper identifies RNA-binding proteins interacting with influenza A virus mRNA and finds that MKRN2 promotes viral mRNA nuclear export by interacting with GLE1.

Conserved induction of distinct antiviral signalling kinetics by primate interferon lambda 4 proteins

This study shows that IFN{lambda}4 induces distinct antiviral signalling kinetics compared to IFN{lambda}1 and 3 in human hepatocyte and intestinal cells, with these effects conserved in non-human primates.

Validation of a low-cost, carbon dioxide-based cryoablation system for percutaneous tumor ablation

This paper validates a low-cost cryoablation system using carbon dioxide for tumor ablation in resource-constrained settings, showing effective necrosis in rat and porcine models.

A Polymorphic Residue That Attenuates the Antiviral Potential of Interferon Lambda 4 in Hominid Lineages

The paper identifies a polymorphic residue in IFN{lambda}4 that reduces its antiviral activity in humans compared to other hominids, contributing to differences in HCV clearance.