Cell BiologybioRxivPreprint
Dichotomous regulation of lysosomes by MYC and TFEB controls hematopoietic stem cell fate
L. Garcia-Prat, K. B. Kaufmann, F. Schneiter…·J. E. Dick
This study shows that lysosomes are regulated by TFEB and MYC to balance catabolic and anabolic processes in hematopoietic stem cells, influencing their fate and activation.
DOI 10.1101/2021.02.24.432720