A recombinant selective drug-resistant M. bovis BCG enhances the bactericidal activity of a second-line tuberculosis regimen
G. Chiwala, Z. Liu, J. N. Mugweru, B. Wang, S. A. Khan, P. N. N. Bate, B. Yusuf, H. M. A. Hameed, C. Fang, Y. Tan, P. Guan, J. Hu, S.-Y. Tan, J. Liu, N. Zhong, T. Zhang
This study develops a drug-resistant recombinant BCG vaccine that enhances second-line TB treatment efficacy in a murine model of drug-resistant tuberculosis.
bioRxiv · Mar 4, 2021Microbiology