Popeye Domain-Containing Protein 1 Scaffolds a Complex of Adenylyl Cyclase 9 and the Two-Pore-Domain Potassium Channel TREK-1 in Heart
T. A. Baldwin, Y. Li, A. Marsden, R. F. R. Schindler, M. Zhang, A. G. Carbajal, M. A. Garcia, V. R. Venna, T. Brand, C. W. Dessauer
The paper identifies POPDC1 as a novel scaffold for AC9 that regulates heart rate by interacting with TREK-1 in an isoproterenol-dependent manner.
bioRxiv · Dec 21, 2021 · PreprintBiochemistry