ImmunologybioRxiv
Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis
T. Carvalheiro, W. Marut, M. I. Pascoal Ramos…·L. Meyaard
The paper investigates how impaired LAIR-1-collagen interaction in fibrosis contributes to inflammation and fibrosis, finding that dysfunctional collagen ligands and matrix metalloproteinases drive disease progression.