Biliatresone treatment of pregnant mice causes changes in bile metabolism and liver inflammation in their offspring
K. Gupta, J. P. Xu, T. Diamond, I. de Jong, A. D. Glass, J. Llewellyn, N. D. Theise, J. D. Winkler, E. M. Behrens, C. Mesaros, R. G. Wells
This study shows that prenatal exposure to low-dose biliatresone in mice leads to altered bile metabolism and liver inflammation in offspring without histological damage.
bioRxiv · Mar 2, 2023 · PreprintPharmacology & Toxicology