Author

T. H. Benedyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. E. Deane· 3 shared S. C. Graham· 3 shared C. M. Crump· 2 shared C. M. Jeffries· 2 shared D. I. Svergun· 2 shared M. Shamin· 2 shared V. Connor· 2 shared A. E. Firth· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMicrobiology

J. E. Deane

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3 papers

Recent·Most cited

MicrobiologybioRxivJun 1, 2022

Herpes simplex virus 1 protein pUL21 stimulates cellular ceramide transport by activating CERT

T. H. Benedyk, V. Connor, E. R. Caroe…·S. C. Graham

This paper shows HSV-1 protein pUL21 activates CERT to increase ceramide to sphingomyelin conversion, but does not affect virus replication or spread.

DOI 10.1016/j.jbc.2022.102589

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivApr 13, 2021

pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

T. H. Benedyk, J. Muenzner, V. Connor…·S. C. Graham

This study identifies pUL21 as a viral phosphatase adaptor that promotes HSV-1 replication and spread by directing dephosphorylation and antagonizing pUS3 kinase activity.

DOI 10.1371/journal.ppat.1009824

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

BiochemistrybioRxivJul 11, 2019

The lipid transfer protein Saposin B does not directly bind CD1d for lipid antigen loading

M. Shamin, T. H. Benedyk, S. C. Graham, J. E. Deane

This study investigates whether Saposin B directly binds CD1d for lipid antigen loading and finds no direct interaction.

DOI 10.12688/wellcomeopenres.15368.1

experimental assayhost-pathogen & immune response

𝕏 PostBluesky