pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread
T. H. Benedyk, J. Muenzner, V. Connor, Y. Han, K. Brown, K. J. Wijesinghe, Y. Zhuang, S. Colaco, G. A. Stoll, O. S. Tutt, S. Svobodova, D. I. Svergun, N. A. Bryant, J. E. Deane, A. E. Firth, , S. C. Graham
This study identifies pUL21 as a viral phosphatase adaptor that promotes HSV-1 replication and spread by directing dephosphorylation and antagonizing pUS3 kinase activity.
bioRxiv · Apr 13, 2021Microbiology