T. Hasegawa

The paper assesses historical and future trends in biodiversity and ecosystem services from 1900 to 2050, finding that biodiversity and regulating services have decreased while provisioning services increased, with climate change expected to worsen future losses.

This study identifies heterogeneous tumor-residing migratory dendritic cells (mRegDCs) that show distinct transcriptional and functional profiles, impacting anti-tumor immune responses.

This study identifies two distinct adrenal macrophage subsets in mice and shows that foamy macrophages regulate corticosteroid production through cholesterol accumulation.

The paper shows extensive genomic overlap between Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis, including shared genes and recombination events, with implications for vaccine development.

This meta-analysis quantifies how heat-tolerant rice cultivars reduce chalky grain percentage under high temperatures, showing a 66% point increase in CG for low HTR cultivars with rising TaHD.

The paper shows that cytotoxic CD4+ T cells eliminate senescent fibroblasts by targeting HCMV-gB antigen expressed on these cells, reducing their accumulation in old skin.

The paper identifies palmitoylation of GSDMD at Cys191/Cys192 as essential for its membrane translocation and pore-forming activity in macrophages.

This study compares nitrogen uptake patterns and yield contributions between dry direct-seeding rice and transplanted rice in a cool temperate climate, finding lower yield in DDSR due to reduced nitrogen use efficiency.

The paper compiles a global dataset of climate change impacts on four crops using existing studies and new literature, providing yield projections under different emission scenarios.

The paper uses lake size and watershed area ratios to predict trophic levels and macrophyte composition in lakes formed by volcanic eruptions, revealing a pattern of hydrarch succession.

This study compares chemical accumulation in fish from direct microplastic exposure versus indirect exposure through prey, finding higher concentrations from prey-mediated ingestion.

This study evaluates heat-induced sterility in rice using canopy micrometeorology data across diverse climates, showing that panicle temperature can accurately predict sterility rates.

The study identifies OsNLP4 as essential for nitrate assimilation gene expression and nitrate-dependent growth in rice.

This study develops a unified simulation model to analyze cancer evolution dynamics and identifies conditions under which different evolutionary processes drive tumor growth.

The paper analyzes microsatellite mutations across 21 cancer types, identifies MSI cancers, and finds factors influencing mutation rates and functional impacts.

This paper describes a protocol for comparing biodiversity and ecosystem services models using harmonized land-use and climate scenarios to assess future impacts and model uncertainties.

The paper introduces RAVEN, a software tool that identifies cancer-specific genes encoding MHC-affine peptides from gene expression data, validated across 50 cancer types.

The paper investigates PKCα translocation in endothelial cells under mechanical stress, finding biphasic movement requiring Ca2+ and DAG for initial translocation and MS channels for secondary translocation.