BiochemistrybioRxiv
Lipid flippase dysfunction as a novel therapeutic target for endosomal anomalies in Alzheimer's disease
N. KANESHIRO, K. MASATO, R. IMAOKA…·N. TAKASUGI
This study identifies lipid flippase dysfunction as a key pathogenic event in Alzheimer's disease and presents a peptide therapy to restore endosomal function.
DOI 10.1016/j.isci.2022.103869